We aim to learn how different types of hormonal birth control may affect the ability of the vagina to fight off infections by altering the immune system, microbiome, and vaginal microenvironment. This study will help us better understand the individual factors that alter a person’s risk profile with contraceptives to help providers conduct individualized contraceptive counseling with their patients.
Study participants must be women under the age of 45 who have a regular menstrual cycle, are HIV-negative, and want to start a hormonal contraceptive. Participants can choose among three types of birth control: Liletta (IUD), Nexplanon (Implant), or Depo-Provera (Shot). They will receive their choice of contraceptive at no cost and will be compensated for their time and effort.
Participants will have up to 10 study visits over a 12-month period at Grady Memorial Hospital.
Visits will include a physical/pelvic exam, urine and blood collection, and swabs of the mouth, vagina, cervix, and rectum. Samples collected will only be identified by a participant number and HIPAA compliance standards are followed.